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+--- Thread: HIV Vaccine Clinical Trial To Begin 2019 (/showthread.php?tid=3578)
HIV Vaccine Clinical Trial To Begin 2019 - Adesewa - 06-05-2018
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The preliminary human trail of an experimental vaccine regiment is anticipated to begin in the second half of 2019, according to a study published yesterday in the journal Nature medicine.
The “broadly neutralising’’ vaccine regiment based on the structure of a vulnerable site on HIV was found to have elicited antibodies in mice, guinea pigs and monkeys that could neutralise dozens of HIV strains from around the world.
The new regiment reflected the approach scientists used to develop an HIV vaccine as they first identify powerful HIV antibodies that can neutralise many strains of the virus.
The researchers had then try to elicit those antibodies with a vaccine based on the structure of the HIV surface protein where the antibodies bind.
The study was led by Peter Kwong, and John Mascola with the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH) under the U.S. Department of Health and Human Services.
“This elegant study is a potentially important step forward in the ongoing quest to develop a safe and effective HIV vaccine,’’ said NIAID Director, Anthony Fauci.
NIH vaccine scientist, Zhou Tongqing, said that this was a revolutionary discovery since in past three decades, no research produced so good a result that elicit “broad neutralising antibiotics” in so many animal models.
Over the past years, HIV researchers have discovered many powerful, naturally occurring antibodies that can prevent multiple HIV strains from infecting human cells in the laboratory.